Cousin frequency distribution from (a) SBP alter, (Gaussian match Roentgen dos having salt sensitive and painful = 0.74 and you will salt unwilling = 0.97) and (b) urinary Na + /K + , (Gaussian fit R dos to own salt sensitive and painful = 0.99 and salt unwilling people = 0.99) on the group of salt sensitive (letter = 71) and you may salt unwilling (n = 119) those with transform out of weightloss input out-of Fat loss Approaches to Stop Blood pressure levels (DASH) large sodium (HS) diet plan so you’re able to Dashboard lower salt (LS) diet plan.
Fellow member class
Certainly one of study users examined, 53% regarding SR and you will 62% of your SS users were female, 51% regarding SR and you will 63% out of SS players was in fact African-Western (Desk 1). More participants was in fact old 29–55 age, college-educated, and operating full time. There had been zero significant differences in standard characteristics to have data participants round the ethnicity otherwise gender either in the fresh SS otherwise SR organizations (Dining table step 1).
Baseline SBP, assessed during the screening visit prior to dietary intervention was significantly higher in SS (137.6 ± 8.7 mmHg) vs. SR participants (132.5 ± 9.6 mmHg; p < 0.05, Table 2). In contrast there was no significant difference in 24 h urinary Na + excretion, 24 h urinary K + excretion and the urinary Na + :K + ratio between SS and SR participants at screening (Table 2). Further, there was no significant effect of sex or ethnicity on these variables, as such subsequent analyses were not adjusted for age or ethnicity. In SS, but not SR participants, each additional g/day in urinary Na + excretion across the range of <2 g/day to 5 g/day resulted in a higher SBP value of approximately 1.0 ± 0.4 mmHg in SBP/g Na + excretion (Fig. 2a). The measures >5 g/day Na+ were not included due to increased sample variability. When assessed by linear regression across the entire range of observed Na + excretion we observed no correlation between urinary Na + excretion and SBP in either SS (R 2 = 0.02) or SR (R 2 = 0.02) participants (Fig. 2b). In both SS and SR participants urinary K + excretion of <1 g/day elevated SBP by 3.9 and 4.8 mmHg respectively vs. SBP values obtained for urinary excretion of 1–1.99gK + /day (Fig. 3a) and the Cohen's D score for the difference in the SBP among the participants with less than 1 g/day versus 1-1.9 g/day of urinary K + excretion showed a medium effect size in both SS (0.45) and the SR (0.49) group. However, when assessed across the entire range of observed K + excretion we observed no correlation between K + excretion and SBP in either SS (R 2 = 0.001) or SR (R 2 = 0.008) participants (Fig. 3b). Further, we observed no association between the urinary Na + :K + ratio and SBP and no impact of urinary K + excretion across any dietary Na + excretion range on SBP in either SS (R 2 = 0.004) or SR (R 2 = 0.002) participants (Fig. 4a, b).
Effect off Dashboard https://datingranking.net/pl/dabble-recenzja/ diet plan on connection out of urinary salt so you can potassium removal proportion having SBP
Within the sub group of SS participants randomly assigned to DASH-Sodium dietary intervention arm (N = 71) there was a significant (p < 0.05) reduction in SBP on the DASH-LS diet compared to the baseline screening SBP value (Table 3). In the sub group of SR participants randomly assigned to the DASH-Sodium intervention (N = 119) there were significant (p < 0.05) reductions in SBP on both the DASH-HS and DASH-LS diets compared to the baseline screening SBP value (Table 3). On the DASH-Sodium diet, following both the LS and HS interventions compared to screening there was a significant (p < 0.05) increase in urinary K + excretion and reduction in the urinary Na + :K + ratio (that was greater during the LS intervention), in both SS and SR participants (Table 3).