Age-standardized properties off 86,149 ladies in the NHS We in the 1994 and you can 94,715 ladies in this new NHS II for the 1995 because of the quintiles out-of magnesium, potassium, and you can calcium supplements intakes step one
Model dos is modified for design 1 and consumption off potassium and calcium supplements (quintiles out of grams/d)
Regarding the multivariate analyses, complete and you will weight loss magnesium https://datingranking.net/kink-dating/ intakes have been inversely associated with the likelihood of full however, ischemic or hemorrhagic stroke ( Table dos). The brand new pooled multivariate RR for total coronary arrest is actually 0.87 (95% CI: 0.78, 0.97; P-trend = 0.07) toward analysis of women throughout the highest having reduced quintiles out of overall magnesium intake; whereas this new pooled multivariate RR to your investigations from higher with reasonable quintiles away from weight loss magnesium intake are 0.81 (95% CI: 0.69, 0.94; P-pattern = 0.001) having overall heart attack. Full potassium consumption is actually inversely associated with the chance of complete however, maybe not ischemic or hemorrhagic stroke ( Dining table step three). For testing of females from the large which have low quintiles of total potassium consumption, the new pooled multivariate RR having full heart attack are 0.89 (95% CI: 0.80, 0.99; P-pattern = 0.01). Multivariate RRs for both magnesium and you can potassium was basically attenuated when the step three nutrition was indeed within the patterns on the other hand (multivariate model dos). You will find no extreme connection ranging from full otherwise fat loss calcium supplements intake and you can full, ischemic, otherwise hemorrhagic heart attack ( Table 4). Multivariate RRs to own full magnesium (Extra Table 1), full potassium (Supplemental Dining table dos), overall calcium supplements (Supplemental Dining table step three), weight-loss magnesium (Extra Dining table cuatro), fat reduction potassium (Supplemental Table 5), and you can diet calcium (Extra Table six) and you can chance of complete, ischemic, and you will hemorrhagic shots for each cohort individually are given regarding the extra topic.
Pooled RRs (95% CIs) off complete, ischemic, and you will hemorrhagic strokes because of the quintiles off complete and you will losing weight magnesium intake in 86,149 women in new NHS We and you will 94,715 women in the fresh new NHS II step one
Values are the n of cases. Cox proportional hazards models were used to estimate RRs and 95% CIs. Model 1 was adjusted for age, calendar year, total calories (quintiles of kcal), BMI (in kg/m 2 ; <25, 25 to <30, or ?30), parental history of heart disease (aged ?60 y), alcohol intake (0, 0 to <5, 5 to <10, 10 to <15, or ?15 g/d), physical activity (<3, 3 to <9, 9 to<18, 18 to <27, or ?27 metabolic equivalent tasks/wk), smoking, postmenopausal hormone therapy, oral contraceptive use (never, past, or current), menopausal status (premenopausal or postmenopausal), aspirin (0 to <2 or ?2 pills/wk), multivitamin, history of hypertension, hypercholesterolemia, diabetes at baseline, and thiazide use (yes or no). NHS, Nurses' Health Study.
Pooled RRs (95% CIs) out-of total, ischemic, and you will hemorrhagic shots by the quintiles out-of total and you may diet magnesium intake within the 86,149 ladies in the fresh new NHS I and 94,715 ladies in the latest NHS II 1
Values are the n of cases. Cox proportional hazards models were used to estimate RRs and 95% CIs. Model 1 was adjusted for age, calendar year, total calories (quintiles of kcal), BMI (in kg/m 2 ; <25, 25 to <30, or ?30), parental history of heart disease (aged ?60 y), alcohol intake (0, 0 to <5, 5 to <10, 10 to <15, or ?15 g/d), physical activity (<3, 3 to <9, 9 to<18, 18 to <27, or ?27 metabolic equivalent tasks/wk), smoking, postmenopausal hormone therapy, oral contraceptive use (never, past, or current), menopausal status (premenopausal or postmenopausal), aspirin (0 to <2 or ?2 pills/wk), multivitamin, history of hypertension, hypercholesterolemia, diabetes at baseline, and thiazide use (yes or no). NHS, Nurses' Health Study.