Recently, the sodium (Na)/potassium (K) ratio was reported to be associated with blood pressure (BP). A Na/K ratio self-monitoring device using spot urine was established recently. Here, we assessed whether the urinary Na/K ratio change measured using the Na/K device was associated with BP change in a health checkup setting. We targeted 12,890 participants who attended the health checkup in Tome City, Miyagi between 2017 and 2018. Tome City introduced urinary Na/K ratio measurements during health checkups since 2017. For each year, we compared the baseline characteristics according to the urinary Na/K ratio and BP level. We assessed the relationship between change in urinary Na/K ratio and BP change using multiple regression analyses adjusted for age, sex, and change in body mass index (BMI) and alcohol intake. The average urinary Na/K ratio was significantly lower in 2018 than in 2017 (5.4 ± 3.0 to 4.9 ± 2.2, P < 0.01). The systolic BP of the participants in 2018 (130.9 ± 17.4 mmHg) was lower than that in 2017 (132.1 ± 17.9 mmHg). Moreover, the change in systolic BP and diastolic BP was positively associated with the change in urinary Na/K ratio. In conclusion, the association of the change in urinary Na/K ratio with hypertension and changes in systolic and diastolic BP can be explained by a change in alcohol intake, BMI, and urinary Na/K ratio. Therefore, measuring the urinary Na/K ratio in community settings is a potential population approach for counteracting hypertension.
Addition
Recently, it was reported that brand new salt (Na)/potassium (K) ratio try of the ÑasualDates ne demek hypertension (BP) when you look at the a cross-sectional research [1,2,step three,4]. This can be questioned because high Na and you will K consumption was known becoming associated with high and you will reduced BP, correspondingly [5,6,7]. Additionally, research has come held on reference opinions and you may circumstances leading to the brand new Na/K proportion previously seasons [8, 9].
Sodium/potassium ratio changes are in the blood pressure transform: odds of populace method for salt/potassium ratio reduced fitness checkup
When you look at the a residential district function, it is sometimes complicated for people to assess the true Na intake just like the Na intake are usually analyzed by 24-h urine collection. Whether or not numerous equations to own quoting Na consumption or K intake having fun with informal put urine was recently established, such equations commonly specific adequate to promote viewpoints for the anyone [10,eleven,12]. Furthermore, since picture requires measuring Na, K, and creatinine account when you look at the a research, it needs several weeks to obtain the results for individuals. Even if participants are aware that salt prevention is good for minimizing BP, he has got not a way regarding examining the Na top.
Recently, good Na/K ratio notice-keeping track of product playing with spot pee try dependent . Though it failed to measure the genuine Na intake height, it does bring viewpoints concerning your urinary Na/K balance in a few minutes. Furthermore, an interventional or observational data with this specific monitor recommended this particular might possibly be a good equipment so you can guess brand new urinary Na/K ratio [13, 14].
Thus, while we have no way to measure the Na/K proportion when you look at the wellness checkup setup, we thought that assessing the latest urinary Na/K ratio within the a healthcare checkup site might have the possibility to include viewpoints towards the general society about their Na/K proportion that can impact effect change, change in step, Na/K proportion cures, and you can BP avoidance. Inside investigation, i examined whether the urinary Na/K proportion change measured to your Na/K proportion aspect equipment try of this BP changes independent from confounding circumstances particularly bmi (BMI) change and change inside liquor consumption and you will compared this new BP height and you can urinary Na/K ratio at society level.
